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CSA Names: JWH-250
CSA Location: Schedule I Section (g) Subsection (7) DEA code 6250
CSA History: S. 3187, 112 Cong., 2nd Sess. added effective 9 Jul 2012
78 FR 664 finalized the prior interim scheduling effective 4 Jan 2013
Names: JWH-250 (primary)
2-(2-Methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone (IUPAC)
Molecular formula: C22H25NO2
Nominal mass: 335
Average mass: 335.4394
Monoisotopic mass: 335.188529
CAS registry number: 864445-43-2
ChemSpider: 23256117
PubChem: 44397540
Wikipedia: JWH-250
Drugs-Forum: JWH-250
Standard InChI: InChI=1S/C22H25NO2/c1-3-4-9-14-23-16-19(18-11-6-7-12-20(18)23)21(24)15-17-10-5-8-13-22(17)25-2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3
SMILES: CCCCCn1cc(c2c1cccc2)C(=O)Cc1ccccc1OC
Tags: cannabinoid,S.3187,USCSA
Property Value Remarks
Property Value Remarks
Location Type Remarks
JWH-250 IR.pdf ATR IR
JWH-250.pdf EI MS Agilent
13634-0424438-GCMS.pdf EI MS Agilent 5973 MSD
JWH250 IRD.pdf GC IRD gas phase
JWH-250 CCCC No.13634.pdf SP-GC-IR Solid Phase IR
JWH-250 edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 13634
LGC THC-1267-10
Lipomed JWH-1356
THC Pharm THC-1267
Toronto Research Chemicals J211500
Title Publication Date Vol. Iss. Page(s) Remarks
A new pyrazole-carboxamide type synthetic cannabinoid AB-CHFUPYCA [N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide] identified in illegal product Forensic Toxicology 2015-07-01 Vol 33 (367-373) Nahoko Uchiyama et al
Consideration of the major cannabinoid agonists 2009-07-00 Advisory Council on the Misuse of Drugs
Understanding the Spice phenomenon 2009-00-00 European Monitoring Centre for Drugs and Drug Addiction
Further consideration of the synthetic cannabinoids 2012-10-18 Advisory Council on the Misuse of Drugs
GC–MS and FTIR evaluation of the six benzoyl-substituted-1-pentylindoles: Isomeric synthetic cannabinoids Talanta 2014-11-01 Vol 129 (171-182) Forrest T. Smitha et al
Detection and identification of the new potential synthetic cannabinoids 1-pentyl-3-(2-iodobenzoyl)indole and 1-pentyl-3-(1-adamantoyl)indole in seized bulk powders in Hungary Forensic Science International 2012-01-01 Vol 214 (27-32) Péter Jankovics et al
Synthetic cannabinoids and cathinones: prevalence and markets Forensic Science Review 2013-03-01 Vol 25 (7-26) Bretteville-Jensen et al
Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety Forensic Science International 2013-03-10 Vol 226 (62-73) Vadim Shevyrin et al
Spice, bath salts, and the U.S. military: the emergence of synthetic cannabinoid receptor agonists and cathinones in the U.S. Armed Forces. 2012-09-01 Loeffler G, Hurst D, Penn A, Yung K
Synthetic cannabinoid and marijuana exposures reported to poison centers Hum Exp Toxicol 2012-10-31 (1006-1011) MB Forrester et al
Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen-1-yl)methanone using GC–MS, NMR analysis and a flash chromato Forensic Science International 2012-07-12 Vol 220 (e17-e22) Bjoern Moosmann et al
Cannabinoid chemistry: an overview Cannabinoids as Therapeutics 2005-01-01 (23-46) Lumír O. Hanuš and Raphael Mechoulam
Synthetic Cannabinoid Isomer Differentiation Journal of CLIC 2011-10-00 Vol 21 (4) Law Enforcement Restricted
GC-MS Differentiation of Three Synthetic Cannabinoid Positional Isomers: JWH-250, JWH-302, and JWH-201 Journal of CLIC 2011-10-00 Vol 21 (4) Law Enforcement Restricted
Identification and Quantitation of Cannabimimetic Compound JWH-250 as an Adulterant in Products Obtained Via the Internet Forensic Toxicol. 2011-00-00 Vol 29 Nakajima et al.
Identification and Quantitation of Two Cannabimimetic Phenylacetylindoles JWH-251 and JWH-250, and Four Cannabimimetic Naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073... Forensic Toxicol. 2011-11-05 Vol 29 Uchiyama et al.
Comprehensive review of the detection methods for synthetic cannabinoids and cathinones Forensic Toxicology 2015-07-01 Vol 33 (175-194) Akira Namera et al
Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles For. Toxicology 2011-01-01 Vol 29 Nahoko Uchiyama et. al.
Phenazepam and cannabinomimetics sold as herbal highs in New Zealand Drug Testing and Analysis 2012-06-01 Vol 4 (6) R. A. F. Couch and H. Madhavaram
Identification of Synthetic Cannabinoids in Herbal Incense Blends in the United States J. For. Sci. 2012-09-01 Vol 57 Barry K. Logan et al
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds Journal of Mass Spectrometry 2010-10-01 Vol 45 (1186-1194) Sebastian Dresen et al
Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in “herbal high” products on the Italian market Forensic Science International 2012-11-30 Vol 223 (e42-e46) Ermanno Valoti et al
Identification of a Novel Cannabimimetic Phenylacetylindole, Cannabipiperidiethanone, as a Designer Drug in a Herbal Product and Its Affinity for Cannabinoid CB1 and CB2 Receptors Chem. Pharm. Bull. 2011-01-01 Vol 59 (1203-1205) Nahoko Uchiyama, Ruri Kikura-Hanajiri, Yukihiro Goda
The emergence and analysis of synthetic cannabinoids Drug Testing and Analysis 2011-08-01 Vol 3 (466-478) Simon Hudson and John Ramsey
Database ID URL
SWGDRUG Mass Spectral Library 1204
Mass Spectra of Designer Drugs 2010
SWGDRUG Monographs JWH-250 Monograph
Cayman Spectral Database
Substance name
Substance name
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