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CSA Names: Mephedrone
CSA Location: Schedule I Section (d) Subsection (36) DEA code 1248
CSA History: S. 3187, 112 Cong., 2nd Sess. added effective 9 Jul 2012
78 FR 664 finalized the prior interim scheduling effective 4 Jan 2013
Names: 2-(Methylamino)-1-(4-methylphenyl)propan-1-one (IUPAC)
Molecular formula: C11H15NO
Nominal mass: 177
Average mass: 177.2429
Monoisotopic mass: 177.115364
CAS registry number: 1189726-22-4
ChemSpider: 21485694
PubChem: 45266826
Wikipedia: Mephedrone
Erowid: 4-Methylmethcathinone / Mephedrone
Drugs-Forum: Mephedrone
Bluelight: Mephedrone
Standard InChI: InChI=1S/C11H15NO/c1-8-4-6-10(7-5-8)11(13)9(2)12-3/h4-7,9,12H,1-3H3
SMILES: CNC(C(=O)c1ccc(cc1)C)C
Tags: cathinone,S.3187,USCSA
Property Value Remarks
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4-methylmethcathinone hcl.pdf ATR IR Thermo Nicolet
mephedrone expanded.pdf EI MS Agilent 5975 MSD
9000940-0432425-GCMS.pdf EI MS nor-mephedrone
11197-0433939-GCMS.pdf EI MS 4-EEC
11223-0435098-GCMS.pdf EI MS 2-MMC
9001082-0435185-GCMS.pdf EI MS 3-EMC
9001081-0435510-GCMS.pdf EI MS 2-EMC
10801-0429260-GCMS.pdf EI MS Agilent 5973 MSD
11224-0435099-GCMS.pdf EI MS 3-MMC
mephedrone acetylated.pdf EI MS Agilent 5975 MSD
Mephedrone EI MS Cayman.pdf Mephedrone EI MS Cayman Spectral Library
Mephedrone edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 11224 (3-MMC)
Cayman Chemical 11197 (4-EEC)
Cayman Chemical 9001081 (2-EMC)
Cayman Chemical 9000940 (nor-mephedrone)
Cayman Chemical 9001082 (3-EMC)
Cayman Chemical 10801
Cayman Chemical 11223 (2-MMC)
Cerilliant M-138
LGC LGCAMP1387.01-01
Lipomed MMC-1252-HC§ion=mediadir&cmd=detail
Sigma Aldrich 92481®ion=US
Tocris Bioscience 4443
Toronto Research Chemicals M224200
Title Publication Date Vol. Iss. Page(s) Remarks
Consideration of the Cathinones 2010-03-00 Advisory Council on the Misuse of Drugs
Screening of seized emerging drugs by ultra-high performance liquid chromatography with photodiode array ultraviolet and mass spectrometric detection. DOI: 10.1016/j.forsciint.2014.01.018 For. Sci. Int. 2014-04-01 Vol 237 L. Li and I. S. Lurie
Analysis and characterization of the novel psychoactive drug Forensic Science International 2014-11-01 Vol 244 (e56-e59) Magdalena Taschwer et al
Forensic Analysis of Cathinones Forensic Science Review 2013-01-01 Vol 25 (48-64) L. Gautam, A. Shanmuganathan, M. D. Cole
Direct analysis in real time mass spectrometry (DART-MS) of “bath salt” cathinone drug mixtures Analyst 2013-01-01 Vol 138 (3424-3432) Ashton D. Lesiak et al
Cathinone derivatives: A review of their chemistry, pharmacology and toxicology Drug Testing and Analysis 2011-01-01 Vol 3 (439-453) John P. Kelly et al
Characterization of Three Methcathinone Anaologs: 4-Methylmethcathinone, Methylone, and bk-MBDB Microgram Journal 2010-03-00 Vol 7 (2) Chad R. Maheux and Catherine R. Copeland, Michael M. Pollard
Analytical Profile of 4-Methylmethcathinone (Law Enforcement Restricted Publication) Journal of CLIC 2010-01-00 Vol 20 (1) Law Enforcement Restricted
Separation and identification of methyl-methcathinones 2011-03-21 IFS, Budapest, Hungary
Analyses of Second-Generation Drug Testing and Analysis 2010-00-00 Vol 2 Brandt et al.
The Analysis of Substituted Cathinones. Part 1: Chemical Analysis of 2-, 3- and 4-methylmethcathinone For. Sci. Int. 2011-00-00 Vol 212 Power et al.
Chemical Analysis of Four Capsules Containing the Controlled Substance Analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone For. Sci. Int. 2010-00-00 Vol 197 Camilleri et al.
The Analysis of Substituted Cathinones. Part 2: An Investigation into the Phenylacetone Based Isomers of 4-methylmethcathinone and N-Ethylcathinone For. Sci. Int. 2011-00-00 Vol 212 McDermott et al.
Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS). DOI:10.1002/jms.3253 Journal of Mass Spectrometry 2013-09-01 Vol 48 (9) Matteo Lanza et al
Discrimination of cathinone regioisomers, sold as ‘legal highs’, by Raman spectroscopy. DOI:10.1002/dta.1518 Drug Testing and Analysis 2014-08-01 Vol 6 (7-8) R. Christie, E. Horan, J. Fox, C. O'Donnell, H. J. Byrne, S. McDermott, J. Power and P. Kavanagh
Identification and differentiation of methcathinone analogs by gas chromatography-mass spectrometry Drug Testing and Analysis 2013-08-01 Vol 5 (8) Kenji Tsujikawa, Toshiyasu Mikuma, Kenji Kuwayama, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata and Hiroyuki Inoue
Keeping pace with NPS releases: fast GC-MS screening of legal high products Drug Testing and Analysis 2013-05-01 Vol 5 (5) Mathieu P. Elie, Leonie E. Elie and Mark G. Baron
'Smoking’ mephedrone: The identification of the pyrolysis products of 4-methylmethcathinone hydrochloride Drug Testing and Analysis 2013-05-01 Vol 5 (5) Pierce Kavanagh, John O'Brien, John D Power, Brian Talbot and Seán D McDermott
Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish Internet company Drug Testing and Analysis 2012-05-01 Vol 4 (5) Lotte A. Reitzel, Petur W. Dalsgaard, Irene B. Müller and Claus Cornett
The analytical investigation of synthetic street drugs containing cathinone analogs For. Sci. Int. 2014-01-01 Vol 234 Amanda M. Leffler, Philip B. Smith, Adriana de Armas, Frank L. Dorman
Microcrystalline identification of selected designer drugs For. Sci. Int. 2012-01-10 Vol 214 Leonie Elie, Mark Baron, Ruth Croxton, Mathieu Elie
Presumptive analysis of 4-methylmethcathinone (mephedrone) using Desorption Electrospray Ionisation - Mass Spectrometry (DESI-MS) Australian J. For. Sci. 2014-02-01 Vol 46 (411-423) Natasha Stojanovska et al
Degradation pathways of 4-methylmethcathinone in alkaline solution and stability of methcathinone analogs in various pH solutions Forensic Science International 2012-07-10 Vol 220 (103-110) Kenji Tsujikawa et al
Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone): A new “legal high” Journal of Pharmaceutical and 2011-09-10 Vol 56 (246-255) Eman Y. Santali et al
An analysis of the ‘legal high’ mephedrone Bioorganic & Medicinal Chemist 2010-07-15 Vol 20 (4135-4139) Simon Gibbons and Mire Zloh
Database ID URL
Mass Spectra of Designer Drugs 2010 11919
SWGDRUG Mass Spectral Library 531
SWGDRUG Monographs 4-Methylmethcathinone Monograph
SWGDRUG Monographs 2-Methylmethcathinone Monograph
SWGDRUG Monographs 3-Methylmethcathinone Monograph
Society of Forensic Toxicologists Designer Drug Monographs Mephedrone Monograph
Mass Spectra of Designer Drugs 2014
NIST/EPA/NIH Mass Spectral Library 2011
Mass Spectral Library of Drugs, Poisons, Pesticides, Pollutants
Cayman Spectral Database
European Project Response to Challenges in Forensic Drug Analyses 4-Methylmethcathinone Monograph
European Project Response to Challenges in Forensic Drug Analyses 3-Methylmethcathinone Monograph
European Project Response to Challenges in Forensic Drug Analyses 2-Methylmethcathinone Monograph
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