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CSA Names: 1-Pentyl-3-[(4-methoxy)-benzoyl]indole
CSA Location: Schedule I Section (g) Subsection (13) DEA code 7104
CSA History: S. 3187, 112 Cong., 2nd Sess. added effective 9 Jul 2012
78 FR 664 finalized the prior interim scheduling effective 4 Jan 2013
Names: RCS-4 (primary)
(4-Methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone (IUPAC)
Molecular formula: C21H23NO2
Nominal mass: 321
Average mass: 321.4128
Monoisotopic mass: 321.172879
CAS registry number:
ChemSpider: 24769418
PubChem: 56841530
Wikipedia: RCS-4
Standard InChI: InChI=1S/C21H23NO2/c1-3-4-7-14-22-15-19(18-8-5-6-9-20(18)22)21(23)16-10-12-17(24-2)13-11-16/h5-6,8-13,15H,3-4,7,14H2,1-2H3
SMILES: CCCCCn1cc(c2c1cccc2)C(=O)c1ccc(cc1)OC
Tags: cannabinoid,S.3187,USCSA
Property Value Remarks
Property Value Remarks
Location Type Remarks
RCS-4 ATR IR.pdf ATR IR Thermo Nicolet
RCS-4 MS.pdf EI MS Agilent 5975 MS
10798-0427940-GCMS.pdf EI MS RCS-4-C4 homolog
10866-0428910-GCMS.pdf EI MS 3-methoxy isomer
10865-0429305-GCMS.pdf EI MS 2-methoxy isomer
10645-0424539-GCMS.pdf EI MS Agilent 5973 MSD
RCS4 IRD.pdf GC IRD gas phase
RCS 4 2-methoxy isomer.pdf SP-GC-IR 2-methoxy isomer (solid phase)
RCS 4 3-methoxy isomer.pdf SP-GC-IR 3-methoxy isomer (solid phase)
RCS-4 edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 10866 (3-methoxy isomer)
Cayman Chemical 10645
Cayman Chemical 10865 (2-methoxy isomer)
LGC THC-1375-10
Lipomed RCS-1493§ion=mediadir&cmd=detail
THC Pharm THC-1375
Toronto Research Chemicals R129200
Title Publication Date Vol. Iss. Page(s) Remarks
A new pyrazole-carboxamide type synthetic cannabinoid AB-CHFUPYCA [N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide] identified in illegal product Forensic Toxicology 2015-07-01 Vol 33 (367-373) Nahoko Uchiyama et al
Consideration of the major cannabinoid agonists 2009-07-00 Advisory Council on the Misuse of Drugs
Understanding the Spice phenomenon 2009-00-00 European Monitoring Centre for Drugs and Drug Addiction
Further consideration of the synthetic cannabinoids 2012-10-18 Advisory Council on the Misuse of Drugs
GC–MS and FTIR evaluation of the six benzoyl-substituted-1-pentylindoles: Isomeric synthetic cannabinoids Talanta 2014-11-01 Vol 129 (171-182) Forrest T. Smitha et al
Detection and identification of the new potential synthetic cannabinoids 1-pentyl-3-(2-iodobenzoyl)indole and 1-pentyl-3-(1-adamantoyl)indole in seized bulk powders in Hungary Forensic Science International 2012-01-01 Vol 214 (27-32) Péter Jankovics et al
Synthetic cannabinoids and cathinones: prevalence and markets Forensic Science Review 2013-03-01 Vol 25 (7-26) Bretteville-Jensen et al
Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety Forensic Science International 2013-03-10 Vol 226 (62-73) Vadim Shevyrin et al
Spice, bath salts, and the U.S. military: the emergence of synthetic cannabinoid receptor agonists and cathinones in the U.S. Armed Forces. 2012-09-01 Loeffler G, Hurst D, Penn A, Yung K
Synthetic cannabinoid and marijuana exposures reported to poison centers Hum Exp Toxicol 2012-10-31 (1006-1011) MB Forrester et al
Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen-1-yl)methanone using GC–MS, NMR analysis and a flash chromato Forensic Science International 2012-07-12 Vol 220 (e17-e22) Bjoern Moosmann et al
Cannabinoid chemistry: an overview Cannabinoids as Therapeutics 2005-01-01 (23-46) Lumír O. Hanuš and Raphael Mechoulam
Identification and quantitation of a benzoylindole (2-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone and a naphthoylindole 1-(5-fluoropentyl-1H-indol-3-yl)-.... Forensic Toxicol 2011-05-12 Nakajima et al.
Identification and Quantitation of two benozylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone.... Forensic Toxicol. 2011-03-29 Vol 29 (2) Nakajima et al.
Cannabinoidmimetika: Massenspektren und IR-ATR-Spektren neuer Verbindungen aus den Jahren 2009/2010 (German) Toxichem Krimtech 2011-00-00 Vol 78(1) Kneisel et al.
Comprehensive review of the detection methods for synthetic cannabinoids and cathinones Forensic Toxicology 2015-07-01 Vol 33 (175-194) Akira Namera et al
Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles For. Toxicology 2013-03-29 Vol 31 Jun’ichi Nakajima et. al.
Identification of Synthetic Cannabinoids in Herbal Incense Blends in the United States J. For. Sci. 2012-09-01 Vol 57 Barry K. Logan et al
The emergence and analysis of synthetic cannabinoids Drug Testing and Analysis 2011-08-01 Vol 3 (466-478) Simon Hudson and John Ramsey
Database ID URL
SWGDRUG Monographs RCS-4 Monograph
SWGDRUG Mass Spectral Library
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