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«Heroin»
CSA Names: Heroin
CSA Location: Schedule I Section (c) Subsection (11) DEA code 9200
CSA History: Scheduled in Public Law 91-513, the original CSA of 1970
Names: (5α,6α)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diyl diacetate (IUPAC)
Molecular formula: C21H23NO5
Nominal mass: 369
Average mass: 369.4110
Monoisotopic mass: 369.157623
CAS registry number: 561-27-3
ChemSpider: 4575379
PubChem: 5462328
Wikipedia: Heroin
Erowid: Heroin
Drugs-Forum: Heroin
Bluelight: Heroin
Standard InChI: InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1
Standard InChI key: GVGLGOZIDCSQPN-PVHGPHFFSA-N
SMILES: CC(=O)O[C@H]1C=C[C@@H]2[C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)C)ccc1OC(=O)C
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heroin base.pdf ATR IR Thermo Nicolet
heroin citrate.pdf ATR IR Thermo Nicolet
heroin hbr.pdf ATR IR Thermo Nicolet
heroin hcl.pdf ATR IR Thermo Nicolet
heroin hi.pdf ATR IR Thermo Nicolet
heroin tartrate.pdf ATR IR Thermo Nicolet
Heroin IR (NIST).pdf Condensed Phase IR Used with the permission of COBLENTZ SOC. Collection (C) 2009 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved.
Heroin MS (NIST).pdf EI MS Used with the permission of NIST Mass Spectrometry Data Center Collection (C) 2008 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved.
heroin ms.pdf EI MS Agilent MSD
Heroin.pdf EI MS UV FTIR Used with permission of CND Analytical. From "Analytical Profiles of the Narcotic Analgesics"
Heroin.bmp GC IRD Used with Permission of Oklahoma State Bureau of Investigation, Forensic Science Center, Controlled Substances Laboratory.
heroin HCl-raman.pdf RAMAN GBI DOFS
Heroin edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 9001543 https://www.caymanchem.com/app/template/Product.vm/catalog/9001543
Cerilliant H-038 http://www.cerilliant.com/shoponline/Item_Details.aspx?itemno=c6c1b5fa-10f8-433f-8253-3e3b1e672ef3
Cerilliant NMID752 http://www.cerilliant.com/shoponline/Item_Details.aspx?itemno=ae9bea06-59c3-4362-a393-0469599471c1
Grace Davison (Alltech) 01365 https://grace.com/pharma-and-biotech/en-us/Pages/Drug-Standards.aspx
LGC CERH-038 http://www.lgcstandards.com/epages/LGC.sf/en_GB/?ObjectPath=/Shops/LGC/Products/CERH-038
Lipomed M-29-HC http://www.lipomed.com/index.php?eid=141§ion=mediadir&cmd=detail
Lipomed M-29-FB http://www.lipomed.com/index.php?eid=17§ion=mediadir&cmd=detail
Sigma Aldrich H159 http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=H159|FLUKA&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC
Sigma Aldrich 67357 http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=67357|FLUKA&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC
THC Pharm THC-1424 https://biochem.thc-pharm.de/product_info.php?cPath=4&products_id=208
Toronto Research Chemicals H281180 http://www.trc-canada.com/detail.php?CatNum=H281180
U.S. Pharmacopeia 1183002 http://store.usp.org/OA_HTML/ibeCCtpItmDspRte.jsp?a=b&item=18716
Title Publication Date Vol. Iss. Page(s) Remarks
IDENTIFICATION OF A HEROIN/CHLOROFORM-IMPURITY REACTION PRODUCT Microgram Bulletin 1994-11-00 Vol 27 (11) J. Clark
DETECTING HEROIN IN HEROIN CITRATE RESIDUES Microgram Bulletin 1994-06-00 Vol 27 (6) Aizenman and Ravreby
Preliminary Investigations into Tris(2,2′-bipyridyl) Ruthenium (III) as a Chemiluminescent Reagent for the Detection of 3,6-Diacetylmorphine (Heroin) on Surfaces Journal of Forensic Sciences 2007-09-00 Vol 52 (5) Kent M. Agg B.Sc. (Hons) et al
Chlorinated Opium Alkaloid Derivatives Produced by the Use of Aqueous Sodium Hypochlorite During the Clandestine Manufacture of Heroin Journal of Forensic Sciences 2009-03-00 Vol 54 (2) John F. Casale B.S. et al
Analysis of Carbohydrates in Seized Heroin Using Capillary Electrophoresis Journal of Forensic Sciences 2006-01-00 Vol 51 (1) Ira Lurie M.S. et al
Neutral Heroin Impurities from Tetrahydrobenzylisoquinoline Alkaloids Journal of Forensic Sciences 2006-03-00 Vol 51 (2) Steven G. Toske Ph.D. et al
Signature Profiling and Classification of Illicit Heroin by GC-MS Analysis of Acidic and Neutral Manufacturing Impurities Journal of Forensic Sciences 2010-01-00 Vol 55 (1) David R. Morello B.S. et al
Chemical Profiling of Heroin Recovered from the North Korean Merchant Vessel Pong Su Journal of Forensic Sciences 2006-05-00 Vol 51 (3) Michael Collins Ph.D. et al
Stable Isotope Analyses of Heroin Seized from the Merchant Vessel Pong Su Journal of Forensic Sciences 2006-05-00 Vol 51 (3) John Casale B.S. et al
CHROMATOGRAPHIC AND MASS SPECTROMETRIC ANALYSIS OF N-METHYL-1-(3,4-METHYLENEDIOXYPHENYL)-2-BUTANAMINE AND REGIOISOMERIC DERIVATIVES (Law Enforcement Restricted Publication) Microgram Bulletin 1995-10-00 Vol 28 (10) F. Taylor Noggle et al.
Etodolac: An Analytical Profile [Heroin Diluent] Microgram Journal 2008-07-00 Vol 6 (3-4) Mandy C. McGehee
The Use of Dipropionylmorphine as a Structurally-Related Internal Standard for Gas Chromatographic Quantitation of Heroin Microgram Journal 2008-01-00 Vol 6 (1-2) Susan C. Kerr, and John F. Casale
IDENTIFICATION OF THIAMINE BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY (Law enforcement restricted publication) (Heroin diluent) Microgram Bulletin 2000-10-00 Vol 33 (10) Raul Morales
SEPARATION OF HEROIN FROM SEVERAL ADULTERANTS IN ILLICIT POWDERS (Law Enforcement Restricted Publication) Microgram Bulletin 1995-09-00 Vol 28 (9) Ronen Burla et al.
Gas chromatographic method validation for the analysis of major components in illicit heroin seized in Malaysia Sci. and Justice J. 2012-03-01 Vol 52 (9-12) Kar-Weng Chan et al
The Identification of Heroin and Three Structurally Related Isoheroins Journal of Forensic Sciences 1989-05-01 Vol 34 (3) Frank Medina
Analytical characterization of isoheroin. Journal of Forensic Sciences 1985-08-01 Vol 30 (3) Beazley W.D.
Characterization of heroin samples by 1H NMR and 2D DOSY 1H NMR For. Sci. Int. 2014-01-01 Vol 234 Stéphane Balayssac et al
Determination of heroin and basic impurities for drug profiling by ultra-high-pressure liquid chromatography For. Sci. Int. 2013-09-10 Vol 231 Ira S. Lurie, Sara E. Driscoll, Sam S. Cathapermal, Sini Panicker
Isolation and purification of heroin from heroin street samples by preparative high performance liquid chromatography For. Sci. Int. 2012-09-10 Vol 221 Zhen Guo, Hui Zheng, Yanzhen Lu, Yun Wei
Analysis of illicit cocaine and heroin samples seized in Luxembourg from 2005–2010 For. Sci. Int. 2011-11-10 Vol 212 Serge Schneider, François Meys
Application of dispersive liquid–liquid microextraction and CE with UV detection for the chiral separation and determination of the multiple illicit drugs on forensic samples For. Sci. Int. 2011-06-15 Vol 209 Liang Meng, Bin Wang, Feng Luo, Guijun Shen, Zhengqiao Wang, Ming Guo
Reliability of ion mobility spectrometry for qualitative analysis of complex, multicomponent illicit drug samples For. Sci. Int. 2011-03-20 Vol 206 Jennifer R. Verkouteren, Jessica L. Staymates
Validation of an ion mobility spectrometry (IMS) method for the detection of heroin and cocaine on incriminated material For. Sci. Int. 2008-05-20 Vol 177 Franz E. Dussy et al
A quick and automated method for profiling heroin samples for tactical intelligence purposes For. Sci. Int. 2007-07-04 Vol 169 Valérie Dufey, Laurence Dujourdy, Fabrice Besacier, Huguette Chaudron
A ‘cold synthesis’ of heroin and implications in heroin signature analysis. Utility of trifluoroacetic/acetic anhydride in the acetylation of morphine For. Sci. Int. 2006-12-20 Vol 164 Luke R. Odell, Jana Skopec, Adam McCluskey
Development of a capillary zone electrophoresis method including a factorial design and simplex optimisation for analysis of amphetamine, amphetamine analogues, cocaine, and heroin For. Sci. Int. 2006-03-10 Vol 157 Johan Dahlén, Sylvia von Eckardstein
Qualitative and quantitative analysis of seized street drug samples and identification of source For. Sci. Int. 2005-09-10 Vol 152 S.P. Sharma, B.C. Purkait, S.C. Lahiri
Heroin profiling: mannitol hexaacetate as an unusual ingredient of some illicit drug seizures For. Sci. Int. 2004-10-04 Vol 145 B.M. El-Haj, A.M. Al-Amri, H.S. Ali
4-Dimethylaminopyridine as a catalyst in heroin synthesis For. Sci. Int. 2002-10-09 Vol 129 S Klemenc
"Heroin impurity profiling A harmonization study for retrospective comparisons" For. Sci. Int. 2000-11-13 Vol 113 L Strömberg et al
Noscapine as an adulterant in illicit heroin samples For. Sci. Int. 2000-01-24 Vol 108 S Klemenc
Heroin profiling: Predicting the country of origin of seized heroin For. Sci. Int. 1998-08-12 Vol 95 A Johnston, L.A King
Comparative chemical analyses of drug samples: general approach and application to heroin For. Sci. Int. 1997-02-28 Vol 85 Fabrice Besacier et al
Particle size analysis of six illicit heroin preparations seized in the U.K. For. Sci. Int. 1996-03-05 Vol 81 P.-J. Holt
Impurities, adulterants and diluents of illicit heroin. Changes during a 12-year period For. Sci. Int. 1994-02-01 Vol 64 Elisabet Kaa
Comparative analysis of illicit heroin samples For. Sci. Int. 1991-07-01 Vol 50 M. Chiarotti, N. Fucci, C. Furnari
Comments on the routine profiling of illicit heroin samples For. Sci. Int. 1990-01-01 Vol 44 Helmut Neumann
The detection and estimation of (A) arsenic in opium, and (B) strychnine in opium and heroin, as a means of identification of their respective sources For. Sci. Int. 1988-02-01 Vol 36 A.R.L. Wijesekera, K.D. Henry, P. Ranasinghe
The routine profiling of forensic heroin samples For. Sci. Int. 1988-11-01 Vol 39 Catherine Barnfield et al
An HPLC method using absorbance rationing for the identification of diamorphine in illicit heroin samples For. Sci. Int. 1988-03-01 Vol 37 P.C. White, A. Etherington, T. Catterick
The illicit preparation of morphine and heroin from pharmaceutical products containing codeine: ‘homebake’ laboratories in New Zealand For. Sci. Int. 1987-07-01 Vol 34 Keith R. Bedford, Susan L. Nolan, René Onrust, Jan D. Siegers
A quantitative densitometric determination of heroin and cocaine samples by high-performance thin-layer chromatography For. Sci. Int. 1986-10-01 Vol 32 E. Della Casa, G. Martone
Impurities, adulterants and diluents of illicit heroin in denmark (jutland and funen) For. Sci. Int. 1986-07-14 Vol 31 Elisabet Kaa, Kaempe Bent
An unequivocal determination of heroin in simulated street drugs by a combination of high-performance liquid chromatography and infrared spectrophotometry using micro-sampling techniques For. Sci. Int. 1978-01-01 Vol 11 D.J. Reuland, W.A. Trinler
Analysis of heroin in relation to illicit drug traffic For. Sci. Int. 1975-08-01 Vol 6 E.P.J. Van Der Slooten, H.J. Van Der Helm
Neutral Heroin Impurities from Tetrahydrobenzylisoquinoline Alkaloids J. For. Sci. 2006-03-01 Vol 51 Steven G. Toske et al
Analysis of Carbohydrates in Seized Heroin Using Capillary Electrophoresis J. For. Sci. 2006-01-01 Vol 51 Ira Lurie, Patrick Hays and Ann Valentino
Trace Analysis of Cocaine and Heroin in Different Customs Scenarios using a Custom-Built Ion Mobility Spectrometer Canadian For. Sci. 1991-01-01 Vol 24 (43-49) Mohinder Chauhan et al
Harmonizing a chemometric procedure for the classification of illicit heroin using manufacturing impurities: preliminary investigation of heroin simulated links Australian J. For. Sci. 2012-10-01 Vol 45 (153-163) Kar Weng Chan, Guan Huat Tan & Richard C.S. Wong
Investigation of illicit heroin seized in Malaysia: physical characteristics and chemical profiling Australian J. For. Sci. 2012-07-01 Vol 44 (353-369) Kar Weng Chan, Guan Huat Tan & Richard C.S. Wong
Chemometric procedures for analyzing trace organic impurities present in street doses of heroin via a constant weight approach Australian J. For. Sci. 2012-07-01 Vol 44 (299-309) Kar Weng Chan, Guan Huat Tan & Richard C.S. Wong
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