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CSA Names: 4-MEC
CSA Location: Schedule I Section (d) Subsection (58) DEA code 1249
Schedule I Section (h) Subsection (11) DEA code 1249
CSA History: 79 FR 4429 proposed to add (for two years) via the emergency scheduling provision of 21 USC 811(h) on 28 Jan 2014
81 FR 11479 proposed to add on 4 Mar 2016
79 FR 12938 added (for two years) via the emergency scheduling provision of 21 USC 811(h) effective 7 Mar 2014
80 FR 14842 renumbered effective 20 Mar 2015
81 FR 11429 extended (for one year) the prior emergency scheduling effective 4 Mar 2016
Names: 4-MEC (primary)
4-Methylethcathinone (secondary)
2-(Ethylamino)-1-(4-methylphenyl)propan-1-one (IUPAC)
Molecular formula: C12H17NO
Nominal mass: 191
Average mass: 191.2695
Monoisotopic mass: 191.131014
CAS registry number: 1225617-18-4
ChemSpider: 25630091
PubChem: 52988259
Wikipedia: 4-Methylethcathinone
Erowid: 4-Methylethcathinone (4-MEC)
Drugs-Forum: (4-MEC)
Standard InChI: InChI=1S/C12H17NO/c1-4-13-10(3)12(14)11-7-5-9(2)6-8-11/h5-8,10,13H,4H2,1-3H3
SMILES: CCNC(C(=O)c1ccc(cc1)C)C
Tags: cathinone,USCSA
Property Value Remarks
Property Value Remarks
Location Type Remarks
4-Methyl-N-Ethylcathinone HCl ATR IR.pdf ATR IR Thermo Nicolet
4-Ethylmethcathinone (4-EMC).pdf EI MS 4-EMC
3-Methylethcathinone (3-MEC).pdf EI MS 3-MEC
2-Ethylmethcathinone (2-EMC).pdf EI MS 2-EMC
11222-0435404-GCMS.pdf EI MS 3-MEC
11228-0434936-GCMS.pdf EI MS 3,4-DMEC
11199-0435482-GCMS.pdf EI MS 2-EEC
11221-0436091-GCMS.pdf EI MS 2-MEC
4MEC msd.pdf EI MS Agilent MSD
9001069-0430408-GCMS.pdf EI MS Agilent 5973 MSD
4-MEC GCMS Cayman.pdf MS Cayman Spectral Library
4-methylethcathinone edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 11221 (2-MEC)
Cayman Chemical 11228 (3,4-DMEC)
Cayman Chemical 11222 (3-MEC)
Cayman Chemical 9001069
Cerilliant M-155
Lipomed MEC-1299-HC§ion=mediadir&cmd=detail
Toronto Research Chemicals E679600
Title Publication Date Vol. Iss. Page(s) Remarks
Consideration of the Cathinones 2010-03-00 Advisory Council on the Misuse of Drugs
Screening of seized emerging drugs by ultra-high performance liquid chromatography with photodiode array ultraviolet and mass spectrometric detection. DOI: 10.1016/j.forsciint.2014.01.018 For. Sci. Int. 2014-04-01 Vol 237 L. Li and I. S. Lurie
Analysis and characterization of the novel psychoactive drug Forensic Science International 2014-11-01 Vol 244 (e56-e59) Magdalena Taschwer et al
Forensic Analysis of Cathinones Forensic Science Review 2013-01-01 Vol 25 (48-64) L. Gautam, A. Shanmuganathan, M. D. Cole
Direct analysis in real time mass spectrometry (DART-MS) of “bath salt” cathinone drug mixtures Analyst 2013-01-01 Vol 138 (3424-3432) Ashton D. Lesiak et al
Cathinone derivatives: A review of their chemistry, pharmacology and toxicology Drug Testing and Analysis 2011-01-01 Vol 3 (439-453) John P. Kelly et al
Prevalence and co-existence of active components of ‘legal highs’ Drug Testing and Analysis 2013-06-01 Vol 5 (6) Dariusz Zuba and Bogumiła Byrska
Analytical profiles of “legal highs” containing cathinones available in the area of Lisbon, Portugal For. Sci. Int. 2014-11-01 Vol 244 Victor M.R. Zancajo, J. Brito, Marta P. Carrasco, M.R. Bronze, Rui Moreira, Alvaro Lopes
The analytical investigation of synthetic street drugs containing cathinone analogs For. Sci. Int. 2014-01-01 Vol 234 Amanda M. Leffler, Philip B. Smith, Adriana de Armas, Frank L. Dorman
Identification and characterization of the new designer drug 4′-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography–tandem mass spectrometr For. Sci. Int. 2011-07-15 Vol 210 Péter Jankovics et al
Analysis of 4-MEC in biological and non-biological material—Three case reports Forensic Science International 2013-05-10 Vol 228 (e11-e15) Dominika Gil et al
Synthesis, full chemical characterisation and development of validated methods for the quantification of the components found in the evolved “legal high” NRG-2 Journal of Pharmaceutical and 2012-03-01 Vol 61 (122-135) Osama I.G. Khreit et al
Database ID URL
SWGDRUG Monographs 2-MEC Monograph
SWGDRUG Monographs 3-MEC Monograph
SWGDRUG Monographs 4-MEC Monograph
Cayman Spectral Database
SWGDRUG Mass Spectral Library
European Project Response to Challenges in Forensic Drug Analyses 4-MEC Monograph
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