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CSA Names: 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one
CSA Location: Schedule I Section (d) Subsection (66) DEA code 1258
Schedule I Section (h) Subsection (19) DEA code 1258
CSA History: 79 FR 4429 proposed to add (for two years) via the emergency scheduling provision of 21 USC 811(h) on 28 Jan 2014
81 FR 11479 proposed to add on 4 Mar 2016
79 FR 12938 added (for two years) via the emergency scheduling provision of 21 USC 811(h) effective 7 Mar 2014
80 FR 14842 renumbered effective 20 Mar 2015
Names: Naphyrone (primary)
Naphthylpyrovalerone (secondary)
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (IUPAC)
Molecular formula: C19H23NO
Nominal mass: 281
Average mass: 281.3920
Monoisotopic mass: 281.177964
CAS registry number: 850352-11-3
ChemSpider: 9418039
PubChem: 11243002
Wikipedia: Naphyrone
Drugs-Forum: Naphthylpyrovalerone
Standard InChI: InChI=1S/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3
SMILES: CCCC(C(=O)c1ccc2c(c1)cccc2)N1CCCC1
Tags: cathinone,USCSA
Property Value Remarks
Property Value Remarks
Location Type Remarks
Naphyrone HCl ATR IR.pdf ATR IR Thermo Nicolet
10517-0434404-GCMS.pdf EI MS Agilent 5973 MSD
Naphyrone msd.pdf EI MS Agilent MSD
11240-04347-GCMS.pdf EI MS 1-naphthyl isomer
Naphyrone JCSO.pdf EI MS Coutesy of MFRC grant SC-12-370 by JCSO (spectra not from verified reference standard)
Naphyrone edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cayman Chemical 11240 (1-naphthyl isomer)
Cayman Chemical 10517
Cerilliant N-067
LGC CAY-10517
Lipomed NPH-1396-HC§ion=mediadir&cmd=detail
Toronto Research Chemicals N377700
Title Publication Date Vol. Iss. Page(s) Remarks
Consideration of the Cathinones 2010-03-00 Advisory Council on the Misuse of Drugs
Screening of seized emerging drugs by ultra-high performance liquid chromatography with photodiode array ultraviolet and mass spectrometric detection. DOI: 10.1016/j.forsciint.2014.01.018 For. Sci. Int. 2014-04-01 Vol 237 L. Li and I. S. Lurie
Analysis and characterization of the novel psychoactive drug Forensic Science International 2014-11-01 Vol 244 (e56-e59) Magdalena Taschwer et al
Forensic Analysis of Cathinones Forensic Science Review 2013-01-01 Vol 25 (48-64) L. Gautam, A. Shanmuganathan, M. D. Cole
Direct analysis in real time mass spectrometry (DART-MS) of “bath salt” cathinone drug mixtures Analyst 2013-01-01 Vol 138 (3424-3432) Ashton D. Lesiak et al
Cathinone derivatives: A review of their chemistry, pharmacology and toxicology Drug Testing and Analysis 2011-01-01 Vol 3 (439-453) John P. Kelly et al
Analyses of Second-Generation Drug Testing and Analysis 2010-00-00 Vol 2 Brandt et al.
The naphyrone story: The Alpha or Beta-naphthyl Isomer? DOI:10.1002/dta.185 Drug Testing and Analysis 2010-10-01 Vol 2 (10) Brandt, Wootton, De Paoli, Freeman
The analytical investigation of synthetic street drugs containing cathinone analogs For. Sci. Int. 2014-01-01 Vol 234 Amanda M. Leffler, Philip B. Smith, Adriana de Armas, Frank L. Dorman
Naphyrone: analytical profile of the new “legal high” substitute for Mephedrone Forensic and Legal Medicine, 2011-02-01 Vol 18 (93) Giorgia De Paoli , Peter D. Maskell and Derrick J. Pounder
Database ID URL
SWGDRUG Monographs Naphyrone Monograph
Cayman Spectral Database
SWGDRUG Mass Spectral Library
European Project Response to Challenges in Forensic Drug Analyses Naphyrone Monograph
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